The starting point is the gathering of data on the hazard of the substance and information on its manufacture and uses, as well as human and environmental exposures occurring in relation to its use and an assessment of physicochemical, human health and environmental hazard. In addition the substance must be evaluated to determine if it's a substance of very high concern (SVHC); a carcinogen, mutagen or reproductive toxin (CMR), persistent, bioaccumulative and toxic (PBT) or very persistent and very bioaccumulative (vPvB).
The hazard assessments are used to classify and label the substance as part of the CSA. A human health hazard assessment determines a derived no-effect level(s) (DNEL) for workers and the general population. A physicochemical hazard assessment assesses the potential effects to human health for explosivity, flammability and oxidising potential. An environmental hazard assessment determines a predicted no effect concentration (PNEC) below which adverse environmental effects in the environmental compartments are not expected to occur.
As only representative we can help you with the preparation of Chemical Safety Assessments/Reports and all aspects of pre-registration and registration.